Welcome!

Open Source Cloud Authors: Elizabeth White, Pat Romanski, Jeev Trika, Ed Featherston, Roger Strukhoff

Blog Feed Post

How the world’s first open source MRI happened

You wouldn’t think that a hang gliding accident could start a revolution in medicine. But when a teenager fell 150 feet into a lake several years ago, the subsequent events that sparked a revolutionary new diagnostic method, what I am calling the first open source MRI. The story is a fascinating look at what one family can accomplish if they keep asking questions and getting the right people into a room to talk to each other.

MRIs are big proprietary machines made by a dozen large equipment manufacturers (such as Siemens, Hitachi and Toshiba) and cost plenty: think of them as what IBM mainframes of the 1980s were when PCs first started entering the corporate ecosystem. You have to train people how to operate them and interpret their scans, and once they are setup, you have to run them more or less continuously to realize the return on your investment. If your hospital or imaging center buys equipment from one vendor, you are pretty much locked into that vendor’s line of accessories and upgrades. And they are designed for very specific diagnostic situations. One of them that they aren’t very good at is looking at spinal cord abnormalities.

This is what Spencer Stein faced when he hit that lake after his hang gliding accident. His fall ended up giving him four spinal fractures, which he found after a week of living with back pain and going to the doctor. That was to be expected, given the height of his fall: he was lucky to be mobile. But what the doctors also found was a cavernous angioma, a series of blood clots inside his spine that he had since birth. The defect wasn’t related to the fall, just something that had been with him all his life, silent and symptom-free. The clots could stay that way, or they could bleed out and paralyze him instantly from the chest down.

Spencer had a tough choice; “I faced a dilemma. Leaving my defect alone, without surgery, could mean permanent loss of all bodily sensation, hideous neurological pain, or loss of functioning and movement in the lower half of my body. Yet an operation on this ultra-important, all-but-inaccessible part of my body could cause any of the same problems. It seemed like a no-win situation.” He wrote this for an article in the local San Diego newspaper this past summer chronicling his adventures.

As Spencer says, the fall was really a gift to learn about his birth defect. Without his fall, it would have never been discovered. So should he get the operation, or leave it alone? It wasn’t an easy decision. First, he had to find a surgeon who did many of these operations: this is a very highly specialized field, and only a few people actually do more than a few spinal operations a year of this nature. Second, many of the doctors Spencer saw didn’t want to do high-risk surgery on someone so young and otherwise so healthy, and said they wouldn’t dare operate. Spencer’s parents left the decision up to him. Can you imagine having to make the call of opening up a spinal cord on an extreme athlete?

Spencer with his parents visited a few of the doctors who specialize in this two-hour procedure, and eventually found one who was willing to proceed with the surgery in Arizona. That was great. But to really understand the structure of the clot, this doctor wanted better, higher-resolution pictures.

Back to the MRIs. Most of the machines that are available to the general public use 1.5 to 3 Tesla magnets (this is a measurement of magnetic force, named after the scientist that did a lot of early work, not the contemporary electric car company). Stein had a series of these MRIs to see what was going on inside his spine. But these images only told part of the story. The way to get to higher res images is to use a bigger magnet, just like our camera phones have a bigger image sensor in them.

It so happens that there is a 7 Tesla magnet at NYU Medical Center, but it was used for medical research unrelated to spinal imaging. No one had ever thought to use this research magnet in this way before.

That’s where Spencer’s dad came into our story. His dad made a few phone calls, and knew some of the leading edge diagnosticians in medical imaging. He managed to bring together people from bio-imaging, neurosurgery, and other clinicians to collaborate on how to use this magnet to take the right kind of spinal pictures.

Spencer’s dad is Lee Stein, someone that I have known for decades for his work in tech. Lee was part of the initial digital payments efforts in the mid-1990s, before there was a PayPal, before there was a Square, when paying for something online using a credit card was new. Now we take these things for granted, but back then Lee and a group of Internet pioneers assembled an elegant way to pay for things using nothing more than email. The effort never took off, but the founders of the firm laid the groundwork for how we pay for things online today.

I have written about Lee before, in another effort that he has been working on for several years called Prize Capital. As a result of this work, Lee became familiar with the TED Med community. (You can watch his TED Talk here :)

He is a very unassuming and modest man for someone who has led some pretty amazing technologic efforts over the years. “Spencer was no longer a patient, but a catalyst for forming a new center at NYU.” When I met up with Lee a few months ago, he told me that he just made a couple of phone calls. Yeah, right. The scan brought together many specialists who were able to cobble together this open source solution in real time, rather than years that it would have normally taken. As you can see in the TED video, the doctors are sitting together, hunched around the MRI monitor, sharing knowledge and ideas on the spot.

As a result of Spencer’s scan and his parents’ efforts, more than $22 million dollars was raised for this new center, including contributions from Siemens, the MRI vendor used at NYU. “It has been a remarkable experience for us as a family to see how NYU has come together to do this,” Lee says in his TED lecture.

The Steins brought together these very highly specialized doctors at NYU, and now they are figuring out ways to use the equipment for a variety of diagnoses of different diseases. It is quite thrilling.

However, the irony of all this is that the 7 Tesla images didn’t help Spencer’s situation. Turns out, the large blood clot concentrates iron molecules in one place, and the large amount of iron deflects the higher-intensity MRI beams so no additional information could be gleaned from these higher res pictures.

But Spencer went ahead with the operation, and fortunately it was successful. He is back in school at Cornell. The Stein family, being who they are, created a prize of $5,000 as part of an ongoing annual business plan competition held by the school.

Their prize is given for the business plan that best addressed issues of disability or environmental sustainability. The first one was given to an idea called EcoFishFeed that raises forager fish for feed at salmon aquaculture farms. The Stein Family Prize will continue to be a part of future Cornell business plan competitions.

It is a fitting testimonial to Spencer’s fall from the sky.


Read the original blog entry...

More Stories By David Strom

David Strom is an international authority on network and Internet technologies. He has written extensively on the topic for 20 years for a wide variety of print publications and websites, such as The New York Times, TechTarget.com, PC Week/eWeek, Internet.com, Network World, Infoworld, Computerworld, Small Business Computing, Communications Week, Windows Sources, c|net and news.com, Web Review, Tom's Hardware, EETimes, and many others.

@ThingsExpo Stories
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
IoT generates lots of temporal data. But how do you unlock its value? You need to discover patterns that are repeatable in vast quantities of data, understand their meaning, and implement scalable monitoring across multiple data streams in order to monetize the discoveries and insights. Motif discovery and deep learning platforms are emerging to visualize sensor data, to search for patterns and to build application that can monitor real time streams efficiently. In his session at @ThingsExpo, ...
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, demonstrated how to move beyond today's coding paradigm and shared the must-have mindsets for removing complexity from the develo...
SYS-CON Events announced today that MangoApps will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device.
The IETF draft standard for M2M certificates is a security solution specifically designed for the demanding needs of IoT/M2M applications. In his session at @ThingsExpo, Brian Romansky, VP of Strategic Technology at TrustPoint Innovation, explained how M2M certificates can efficiently enable confidentiality, integrity, and authenticity on highly constrained devices.
SYS-CON Events announced today that LeaseWeb USA, a cloud Infrastructure-as-a-Service (IaaS) provider, will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. LeaseWeb is one of the world's largest hosting brands. The company helps customers define, develop and deploy IT infrastructure tailored to their exact business needs, by combining various kinds cloud solutions.
Early adopters of IoT viewed it mainly as a different term for machine-to-machine connectivity or M2M. This is understandable since a prerequisite for any IoT solution is the ability to collect and aggregate device data, which is most often presented in a dashboard. The problem is that viewing data in a dashboard requires a human to interpret the results and take manual action, which doesn’t scale to the needs of IoT.
Internet of @ThingsExpo has announced today that Chris Matthieu has been named tech chair of Internet of @ThingsExpo 2016 Silicon Valley. The 6thInternet of @ThingsExpo will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
“delaPlex Software provides software outsourcing services. We have a hybrid model where we have onshore developers and project managers that we can place anywhere in the U.S. or in Europe,” explained Manish Sachdeva, CEO at delaPlex Software, in this SYS-CON.tv interview at @ThingsExpo, held June 7-9, 2016, at the Javits Center in New York City, NY.
When people aren’t talking about VMs and containers, they’re talking about serverless architecture. Serverless is about no maintenance. It means you are not worried about low-level infrastructural and operational details. An event-driven serverless platform is a great use case for IoT. In his session at @ThingsExpo, Animesh Singh, an STSM and Lead for IBM Cloud Platform and Infrastructure, will detail how to build a distributed serverless, polyglot, microservices framework using open source tec...
"My role is working with customers, helping them go through this digital transformation. I spend a lot of time talking to banks, big industries, manufacturers working through how they are integrating and transforming their IT platforms and moving them forward," explained William Morrish, General Manager Product Sales at Interoute, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
A critical component of any IoT project is what to do with all the data being generated. This data needs to be captured, processed, structured, and stored in a way to facilitate different kinds of queries. Traditional data warehouse and analytical systems are mature technologies that can be used to handle certain kinds of queries, but they are not always well suited to many problems, particularly when there is a need for real-time insights.
IoT is rapidly changing the way enterprises are using data to improve business decision-making. In order to derive business value, organizations must unlock insights from the data gathered and then act on these. In their session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, and Peter Shashkin, Head of Development Department at EastBanc Technologies, discussed how one organization leveraged IoT, cloud technology and data analysis to improve customer experiences and effi...
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform and how we integrate our thinking to solve complicated problems. In his session at 19th Cloud Expo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm ...
From wearable activity trackers to fantasy e-sports, data and technology are transforming the way athletes train for the game and fans engage with their teams. In his session at @ThingsExpo, will present key data findings from leading sports organizations San Francisco 49ers, Orlando Magic NBA team. By utilizing data analytics these sports orgs have recognized new revenue streams, doubled its fan base and streamlined costs at its stadiums. John Paul is the CEO and Founder of VenueNext. Prior ...