Welcome!

Open Source Cloud Authors: Elizabeth White, Ed Featherston, Roger Strukhoff, Pat Romanski, Yeshim Deniz

Blog Feed Post

How the world’s first open source MRI happened

You wouldn’t think that a hang gliding accident could start a revolution in medicine. But when a teenager fell 150 feet into a lake several years ago, the subsequent events that sparked a revolutionary new diagnostic method, what I am calling the first open source MRI. The story is a fascinating look at what one family can accomplish if they keep asking questions and getting the right people into a room to talk to each other.

MRIs are big proprietary machines made by a dozen large equipment manufacturers (such as Siemens, Hitachi and Toshiba) and cost plenty: think of them as what IBM mainframes of the 1980s were when PCs first started entering the corporate ecosystem. You have to train people how to operate them and interpret their scans, and once they are setup, you have to run them more or less continuously to realize the return on your investment. If your hospital or imaging center buys equipment from one vendor, you are pretty much locked into that vendor’s line of accessories and upgrades. And they are designed for very specific diagnostic situations. One of them that they aren’t very good at is looking at spinal cord abnormalities.

This is what Spencer Stein faced when he hit that lake after his hang gliding accident. His fall ended up giving him four spinal fractures, which he found after a week of living with back pain and going to the doctor. That was to be expected, given the height of his fall: he was lucky to be mobile. But what the doctors also found was a cavernous angioma, a series of blood clots inside his spine that he had since birth. The defect wasn’t related to the fall, just something that had been with him all his life, silent and symptom-free. The clots could stay that way, or they could bleed out and paralyze him instantly from the chest down.

Spencer had a tough choice; “I faced a dilemma. Leaving my defect alone, without surgery, could mean permanent loss of all bodily sensation, hideous neurological pain, or loss of functioning and movement in the lower half of my body. Yet an operation on this ultra-important, all-but-inaccessible part of my body could cause any of the same problems. It seemed like a no-win situation.” He wrote this for an article in the local San Diego newspaper this past summer chronicling his adventures.

As Spencer says, the fall was really a gift to learn about his birth defect. Without his fall, it would have never been discovered. So should he get the operation, or leave it alone? It wasn’t an easy decision. First, he had to find a surgeon who did many of these operations: this is a very highly specialized field, and only a few people actually do more than a few spinal operations a year of this nature. Second, many of the doctors Spencer saw didn’t want to do high-risk surgery on someone so young and otherwise so healthy, and said they wouldn’t dare operate. Spencer’s parents left the decision up to him. Can you imagine having to make the call of opening up a spinal cord on an extreme athlete?

Spencer with his parents visited a few of the doctors who specialize in this two-hour procedure, and eventually found one who was willing to proceed with the surgery in Arizona. That was great. But to really understand the structure of the clot, this doctor wanted better, higher-resolution pictures.

Back to the MRIs. Most of the machines that are available to the general public use 1.5 to 3 Tesla magnets (this is a measurement of magnetic force, named after the scientist that did a lot of early work, not the contemporary electric car company). Stein had a series of these MRIs to see what was going on inside his spine. But these images only told part of the story. The way to get to higher res images is to use a bigger magnet, just like our camera phones have a bigger image sensor in them.

It so happens that there is a 7 Tesla magnet at NYU Medical Center, but it was used for medical research unrelated to spinal imaging. No one had ever thought to use this research magnet in this way before.

That’s where Spencer’s dad came into our story. His dad made a few phone calls, and knew some of the leading edge diagnosticians in medical imaging. He managed to bring together people from bio-imaging, neurosurgery, and other clinicians to collaborate on how to use this magnet to take the right kind of spinal pictures.

Spencer’s dad is Lee Stein, someone that I have known for decades for his work in tech. Lee was part of the initial digital payments efforts in the mid-1990s, before there was a PayPal, before there was a Square, when paying for something online using a credit card was new. Now we take these things for granted, but back then Lee and a group of Internet pioneers assembled an elegant way to pay for things using nothing more than email. The effort never took off, but the founders of the firm laid the groundwork for how we pay for things online today.

I have written about Lee before, in another effort that he has been working on for several years called Prize Capital. As a result of this work, Lee became familiar with the TED Med community. (You can watch his TED Talk here :)

He is a very unassuming and modest man for someone who has led some pretty amazing technologic efforts over the years. “Spencer was no longer a patient, but a catalyst for forming a new center at NYU.” When I met up with Lee a few months ago, he told me that he just made a couple of phone calls. Yeah, right. The scan brought together many specialists who were able to cobble together this open source solution in real time, rather than years that it would have normally taken. As you can see in the TED video, the doctors are sitting together, hunched around the MRI monitor, sharing knowledge and ideas on the spot.

As a result of Spencer’s scan and his parents’ efforts, more than $22 million dollars was raised for this new center, including contributions from Siemens, the MRI vendor used at NYU. “It has been a remarkable experience for us as a family to see how NYU has come together to do this,” Lee says in his TED lecture.

The Steins brought together these very highly specialized doctors at NYU, and now they are figuring out ways to use the equipment for a variety of diagnoses of different diseases. It is quite thrilling.

However, the irony of all this is that the 7 Tesla images didn’t help Spencer’s situation. Turns out, the large blood clot concentrates iron molecules in one place, and the large amount of iron deflects the higher-intensity MRI beams so no additional information could be gleaned from these higher res pictures.

But Spencer went ahead with the operation, and fortunately it was successful. He is back in school at Cornell. The Stein family, being who they are, created a prize of $5,000 as part of an ongoing annual business plan competition held by the school.

Their prize is given for the business plan that best addressed issues of disability or environmental sustainability. The first one was given to an idea called EcoFishFeed that raises forager fish for feed at salmon aquaculture farms. The Stein Family Prize will continue to be a part of future Cornell business plan competitions.

It is a fitting testimonial to Spencer’s fall from the sky.


Read the original blog entry...

More Stories By David Strom

David Strom is an international authority on network and Internet technologies. He has written extensively on the topic for 20 years for a wide variety of print publications and websites, such as The New York Times, TechTarget.com, PC Week/eWeek, Internet.com, Network World, Infoworld, Computerworld, Small Business Computing, Communications Week, Windows Sources, c|net and news.com, Web Review, Tom's Hardware, EETimes, and many others.

@ThingsExpo Stories
Cognitive Computing is becoming the foundation for a new generation of solutions that have the potential to transform business. Unlike traditional approaches to building solutions, a cognitive computing approach allows the data to help determine the way applications are designed. This contrasts with conventional software development that begins with defining logic based on the current way a business operates. In her session at 18th Cloud Expo, Judith S. Hurwitz, President and CEO of Hurwitz & ...
In his general session at 18th Cloud Expo, Lee Atchison, Principal Cloud Architect and Advocate at New Relic, discussed cloud as a ‘better data center’ and how it adds new capacity (faster) and improves application availability (redundancy). The cloud is a ‘Dynamic Tool for Dynamic Apps’ and resource allocation is an integral part of your application architecture, so use only the resources you need and allocate /de-allocate resources on the fly.
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives. Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, wh...
19th Cloud Expo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy. Meanwhile, 94% of enterpri...
SYS-CON Events announced today that Bsquare has been named “Silver Sponsor” of SYS-CON's @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. For more than two decades, Bsquare has helped its customers extract business value from a broad array of physical assets by making them intelligent, connecting them, and using the data they generate to optimize business processes.
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 19th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The Internet of Things (IoT) is the most profound change in personal and enterprise IT since the creation of the Worldwide Web more than 20 years ago. All major researchers estimate there will be tens of billions devices - comp...
There is little doubt that Big Data solutions will have an increasing role in the Enterprise IT mainstream over time. Big Data at Cloud Expo - to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA - has announced its Call for Papers is open. Cloud computing is being adopted in one form or another by 94% of enterprises today. Tens of billions of new devices are being connected to The Internet of Things. And Big Data is driving this bus. An exponential increase is...
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
Cloud computing is being adopted in one form or another by 94% of enterprises today. Tens of billions of new devices are being connected to The Internet of Things. And Big Data is driving this bus. An exponential increase is expected in the amount of information being processed, managed, analyzed, and acted upon by enterprise IT. This amazing is not part of some distant future - it is happening today. One report shows a 650% increase in enterprise data by 2020. Other estimates are even higher....
The cloud market growth today is largely in public clouds. While there is a lot of spend in IT departments in virtualization, these aren’t yet translating into a true “cloud” experience within the enterprise. What is stopping the growth of the “private cloud” market? In his general session at 18th Cloud Expo, Nara Rajagopalan, CEO of Accelerite, explored the challenges in deploying, managing, and getting adoption for a private cloud within an enterprise. What are the key differences between wh...
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 19th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world and ThingsExpo Silicon Valley Call for Papers is now open.
It is one thing to build single industrial IoT applications, but what will it take to build the Smart Cities and truly society changing applications of the future? The technology won’t be the problem, it will be the number of parties that need to work together and be aligned in their motivation to succeed. In his Day 2 Keynote at @ThingsExpo, Henrik Kenani Dahlgren, Portfolio Marketing Manager at Ericsson, discussed how to plan to cooperate, partner, and form lasting all-star teams to change t...
Connected devices and the industrial internet are growing exponentially every year with Cisco expecting 50 billion devices to be in operation by 2020. In this period of growth, location-based insights are becoming invaluable to many businesses as they adopt new connected technologies. Knowing when and where these devices connect from is critical for a number of scenarios in supply chain management, disaster management, emergency response, M2M, location marketing and more. In his session at @Th...
SYS-CON Events announced today that ReadyTalk, a leading provider of online conferencing and webinar services, has been named Vendor Presentation Sponsor at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. ReadyTalk delivers audio and web conferencing services that inspire collaboration and enable the Future of Work for today’s increasingly digital and mobile workforce. By combining intuitive, innovative tec...
Amazon has gradually rolled out parts of its IoT offerings, but these are just the tip of the iceberg. In addition to optimizing their backend AWS offerings, Amazon is laying the ground work to be a major force in IoT - especially in the connected home and office. In his session at @ThingsExpo, Chris Kocher, founder and managing director of Grey Heron, explained how Amazon is extending its reach to become a major force in IoT by building on its dominant cloud IoT platform, its Dash Button strat...
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life sett...
There are several IoTs: the Industrial Internet, Consumer Wearables, Wearables and Healthcare, Supply Chains, and the movement toward Smart Grids, Cities, Regions, and Nations. There are competing communications standards every step of the way, a bewildering array of sensors and devices, and an entire world of competing data analytics platforms. To some this appears to be chaos. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, Bradley Holt, Developer Advocate a...
industrial company for a multi-year contract initially valued at over $4.0 million. In addition to DataV software, Bsquare will also provide comprehensive systems integration, support and maintenance services. DataV leverages advanced data analytics, predictive reasoning, data-driven diagnostics, and automated orchestration of remediation actions in order to improve asset uptime while reducing service and warranty costs.
Vidyo, Inc., has joined the Alliance for Open Media. The Alliance for Open Media is a non-profit organization working to define and develop media technologies that address the need for an open standard for video compression and delivery over the web. As a member of the Alliance, Vidyo will collaborate with industry leaders in pursuit of an open and royalty-free AOMedia Video codec, AV1. Vidyo’s contributions to the organization will bring to bear its long history of expertise in codec technolo...